A Case Study on Integrating a New Key Event Into an Existing Adverse Outcome Pathway on Oxidative DNA Damage: Challenges and Approaches in a Data-Rich Area

Adverse outcome pathways (AOPs) synthesize toxicological information to convey and weigh evidence in an accessible format. AOPs are constructed in modules that include key events (KEs) and key event relationships (KERs). This modular structure facilitates AOP expansion and network development. AOP d...

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Detalles Bibliográficos
Autores principales: Huliganga, Elizabeth, Marchetti, Francesco, O’Brien, Jason M., Chauhan, Vinita, Yauk, Carole L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097222/
https://www.ncbi.nlm.nih.gov/pubmed/35573276
http://dx.doi.org/10.3389/ftox.2022.827328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097222/
https://www.ncbi.nlm.nih.gov/pubmed/35573276
http://dx.doi.org/10.3389/ftox.2022.827328

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