Multiscale Simulations Identify Origins of Differential Carbapenem Hydrolysis by the OXA-48 β-Lactamase

[Image: see text] OXA-48 β-lactamases are frequently encountered in bacterial infections caused by carbapenem-resistant Gram-negative bacteria. Due to the importance of carbapenems in the treatment of healthcare-associated infections and the increasingly wide dissemination of OXA-48-like enzymes on...

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Detalles Bibliográficos
Autores principales: Hirvonen, Viivi H. A., Weizmann, Tal Moshe, Mulholland, Adrian J., Spencer, James, van der Kamp, Marc W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097296/
https://www.ncbi.nlm.nih.gov/pubmed/35571461
http://dx.doi.org/10.1021/acscatal.1c05694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097296/
https://www.ncbi.nlm.nih.gov/pubmed/35571461
http://dx.doi.org/10.1021/acscatal.1c05694

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