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RHAMNETIN IS A BETTER INHIBITOR OF SARS-COV-2 2’-O-METHYLTRANSFERASE THAN DOLUTEGRAVIR: A COMPUTATIONAL PREDICTION

BACKGROUND: The 2’-O-methyltransferase is responsible for the capping of SARS-CoV-2 mRNA and consequently the evasion of the host’s immune system. This study aims at identifying prospective natural inhibitors of the active site of SARS-CoV-2 2’O-methyltransferase (2’-OMT) through an in silico approa...

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Detalles Bibliográficos
Autores principales: Rowaiye, Adekunle B., Oli, Angus Nnamdi, Onuh, Olukemi A., Emeter, Nkoli W, Bur, Doofan, Obideyi, Oluwaseun A., Dayisi, Oluyomi Cornelius, Akpa, Jude N., Birah, Lovelyn, Omaka¹, Edward E., Iseghohi¹, Frances Otibhor, Otitoju, Akinbobola Peace, Uzor, Philip F., Okoyeh, Jude Nnaemeka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: African Traditional Herbal Medicine Supporters Initiative (ATHMSI) 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097307/
https://www.ncbi.nlm.nih.gov/pubmed/35582066
http://dx.doi.org/10.21010/Ajid.v16i2.9