Cargando…

RHAMNETIN IS A BETTER INHIBITOR OF SARS-COV-2 2’-O-METHYLTRANSFERASE THAN DOLUTEGRAVIR: A COMPUTATIONAL PREDICTION

BACKGROUND: The 2’-O-methyltransferase is responsible for the capping of SARS-CoV-2 mRNA and consequently the evasion of the host’s immune system. This study aims at identifying prospective natural inhibitors of the active site of SARS-CoV-2 2’O-methyltransferase (2’-OMT) through an in silico approa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rowaiye, Adekunle B., Oli, Angus Nnamdi, Onuh, Olukemi A., Emeter, Nkoli W, Bur, Doofan, Obideyi, Oluwaseun A., Dayisi, Oluyomi Cornelius, Akpa, Jude N., Birah, Lovelyn, Omaka¹, Edward E., Iseghohi¹, Frances Otibhor, Otitoju, Akinbobola Peace, Uzor, Philip F., Okoyeh, Jude Nnaemeka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	African Traditional Herbal Medicine Supporters Initiative (ATHMSI) 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097307/ https://www.ncbi.nlm.nih.gov/pubmed/35582066 http://dx.doi.org/10.21010/Ajid.v16i2.9

Ejemplares similares

Identifying immunodominant multi-epitopes from the envelope glycoprotein of the Lassa mammarenavirus as vaccine candidate for Lassa fever
por: Rowaiye, Adekunle Babajide, et al.
Publicado: (2022)

The pandemic COVID-19: a tale of viremia, cellular oxidation and immune dysfunction
por: Rowaiye, Adekunle Babajide, et al.
Publicado: (2020)

Identifying potential natural inhibitors of Brucella melitensis Methionyl-tRNA synthetase through an in-silico approach
por: Rowaiye, Adekunle Babajide, et al.
Publicado: (2022)

Immunoinformatics and Vaccine Development: An Overview
por: Oli, Angus Nnamdi, et al.
Publicado: (2020)

Rhamnetin ameliorates non-alcoholic steatosis and hepatocellular carcinoma in vitro
por: Shatta, Mahmoud A., et al.
Publicado: (2022)

Evaluation of Rhamnetin as an Inhibitor of the Pharmacological Effect of Secretory Phospholipase A2
por: Novo Belchor, Mariana, et al.
Publicado: (2017)

Exploiting DNA Ligase III addiction of multiple myeloma by flavonoid Rhamnetin
por: Caracciolo, Daniele, et al.
Publicado: (2022)

The Pharmacobiochemical Effects of Ethanol Extract of Justicia secunda Vahl Leaves in Rattus Norvegicus
por: Onochie, Anthony U, et al.
Publicado: (2020)

The Bacteriology and Its Virulence Factors in Neonatal Infections: Threats to Child Survival Strategies
por: Ejiofor, Obiora Shedrach, et al.
Publicado: (2018)

Winning the War against Multi-Drug Resistant Diarrhoeagenic Bacteria
por: Enemchukwu, Chizoba Mercy, et al.
Publicado: (2019)

Emergency medicine: magnesium sulphate injections and their pharmaceutical quality concerns
por: Oli, Angus Nnamdi, et al.
Publicado: (2021)

Cytoprotective effect of rhamnetin on miconazole-induced H9c2 cell damage
por: Lee, Kang Pa, et al.
Publicado: (2015)

Carbapenem-Resistant Enterobacteriaceae Posing a Dilemma in Effective Healthcare Delivery
por: Oli, Angus Nnamdi, et al.
Publicado: (2019)

Protective Effects of Rhamnetin in Carbapenem-Resistant Acinetobacter baumannii-Induced Sepsis Model and the Underlying Mechanism
por: Kim, Minju, et al.
Publicado: (2023)

Rhamnetin attenuates cognitive deficit and inhibits hippocampal inflammatory response and oxidative stress in rats with traumatic brain injury
por: Zhang, Wei, et al.
Publicado: (2015)

Attenuating the Effects of Novel COVID-19 (SARS-CoV-2) Infection-Induced Cytokine Storm and the Implications
por: Rowaiye, Adekunle Babajide, et al.
Publicado: (2021)

Regioselective O-Derivatization of Quercetin via Ester Intermediates. An Improved Synthesis of Rhamnetin and Development of a New Mitochondriotropic Derivative
por: Mattarei, Andrea, et al.
Publicado: (2010)

Anti-Inflammatory Effects of Rhamnetin on Bradykinin-Induced Matrix Metalloproteinase-9 Expression and Cell Migration in Rat Brain Astrocytes
por: Yang, Chien-Chung, et al.
Publicado: (2022)

Hysteroscopy Findings after Two Previous Failed In vitro Fertilisation Cycles: A Case for Routine Hysteroscopy before In vitro Fertilisation?
por: Okohue, Jude Ehiabhi, et al.
Publicado: (2020)

Rhamnetin, a Natural Flavonoid, Ameliorates Organ Damage in a Mouse Model of Carbapenem-Resistant Acinetobacter baumannii-Induced Sepsis
por: Lee, Hyeju, et al.
Publicado: (2022)

Bacteriological qualities and antibiogram studies of bacteria from "suya" and smoked fish (Clarias gariepinus) in Dutsin-Ma, Katsina State, Nigeria
por: Adesoji, Ayodele Timilehin, et al.
Publicado: (2019)

Sclero-Hyalinized Low-Grade Appendiceal Mucinous Neoplasm Clinically Mimicking an Ovarian Mass
por: Onyishi, Nnaemeka Thaddeus, et al.
Publicado: (2022)

Biosurfactant Production Using Mutant Strains of Pseudomonas aeruginosa and Bacillus subtilis from Agro-industrial Wastes
por: Adejumo, Samson A., et al.
Publicado: (2021)

Community acceptance and willingness to pay for hypothetical COVID-19 vaccines in a developing country: a web-based nationwide study in Nigeria
por: Okafor, Ukamaka Gladys, et al.
Publicado: (2021)

Prevalence of multi-drug resistant Pseudomonas aeruginosa isolated from selected residential sewages in Dutsin-Ma, Katsina State, Nigeria
por: Adesoji, Ayodele Timilehin, et al.
Publicado: (2023)

Regulation of Immunity in Breast Cancer
por: Edechi, Chidalu A., et al.
Publicado: (2019)

A Review of the Uses and Medicinal Properties of Dennettia tripetala (Pepperfruit)
por: Iseghohi, Sylvia Oghogho
Publicado: (2015)

Cancer stem cells may contribute to the difficulty in treating cancer
por: Iseghohi, Sylvia Oghogho
Publicado: (2016)

Co-Efficient Vector Based Differential Distributed Quasi-Orthogonal Space Time Frequency Coding
por: Nwanekezie, Nnamdi, et al.
Publicado: (2023)

Crystal Structure of the Catalytic Domain of a Botulinum Neurotoxin Homologue from Enterococcus faecium: Potential Insights into Substrate Recognition
por: Gregory, Kyle S., et al.
Publicado: (2023)

Prediction of HIV-1 protease cleavage site from octapeptide sequence information using selected classifiers and hybrid descriptors
por: Onah, Emmanuel, et al.
Publicado: (2022)

3517 Cancer-Related Pain is a Predictor of In-hospital Opioid Overdose among Postoperative patients
por: Onyeakusi, Nnaemeka E, et al.
Publicado: (2019)

How ageing increases cancer susceptibility: A tale of two opposing yet synergistic views
por: Iseghohi, Sylvia Oghogho, et al.
Publicado: (2016)

Igbo Speech Surrogacy: Preliminary Findings Based on the Oja Flute
por: Carter-Ényì, Aaron, et al.
Publicado: (2021)

Crosspteryx fibrifuga leaf extract enhances host resistance to Trypanosoma congolense infection in mice by regulating host immune response and disrupting the activity of parasite superoxide dismutase enzyme
por: Ikeogu, Nnamdi, et al.
Publicado: (2023)

SARS-CoV-2 Seropositivity in Asymptomatic Frontline Health Workers in Ibadan, Nigeria
por: Olayanju, Olatunde, et al.
Publicado: (2021)

Leishmania Immunity: Advancing Immunotherapy and Vaccine Development
por: Ikeogu, Nnamdi M., et al.
Publicado: (2020)

Recent advances in hydrophilic modification and performance of polyethersulfone (PES) membrane via additive blending
por: Otitoju, Tunmise Ayode, et al.
Publicado: (2018)

THE PREVALENCE LIVER FUNCTION AND IMMUNOLOGIC STATUS OF CHILDREN WITH HIV AND HEPATITIS B VIRUS COINFECTION IN ENUGU, NIGERIA
por: Davidson, Uleanya Nwachinemere, et al.
Publicado: (2016)

Prioritizing preferred traits in the yam value chain in Nigeria: a gender situation analysis
por: Okoye, Benjamin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8brtaki0mjuas2qnkb57b9trhb