VMP1 and TMEM41B are essential for DMV formation during β-coronavirus infection

β-coronaviruses reshape host cell endomembranes to form double-membrane vesicles (DMVs) for genome replication and transcription. Ectopically expressed viral nonstructural proteins nsp3 and nsp4 interact to zipper and bend the ER for DMV biogenesis. Genome-wide screens revealed the autophagy protein...

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Detalles Bibliográficos
Autores principales: Ji, Mingming, Li, Meng, Sun, Long, Zhao, Hongyu, Li, Ying, Zhou, Lulu, Yang, Zhenni, Zhao, Xin, Qu, Wenyan, Xue, Hanbing, Zheng, Ze, Li, Yiming, Deng, Hongyu, Zhao, Yan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097365/
https://www.ncbi.nlm.nih.gov/pubmed/35536318
http://dx.doi.org/10.1083/jcb.202112081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097365/
https://www.ncbi.nlm.nih.gov/pubmed/35536318
http://dx.doi.org/10.1083/jcb.202112081

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