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Nanomolar EP4 receptor potency and expression of eicosanoid-related enzymes in normal appearing colonic mucosa from patients with colorectal neoplasia

BACKGROUND: Aberrations in cyclooxygenase and lipoxygenase (LOX) pathways in non-neoplastic, normal appearing mucosa from patients with colorectal neoplasia (CRN), could hypothetically qualify as predisposing CRN-markers. METHODS: To test this hypothesis, biopsies were obtained during colonoscopy fr...

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Detalles Bibliográficos
Autores principales: Feddersen, Ulrike Ries, Hendel, Sebastian Kjærgaard, Berner-Hansen, Mark Alexander, Jepps, Thomas Andrew, Berner-Hansen, Mark, Bindslev, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097415/
https://www.ncbi.nlm.nih.gov/pubmed/35549670
http://dx.doi.org/10.1186/s12876-022-02311-z