PRDM1 Drives Human Primary T Cell Hyporesponsiveness by Altering the T Cell Transcriptome and Epigenome

T cell hyporesponsiveness is crucial for the functional immune system and prevents the damage induced by alloreactive T cells in autoimmune pathology and transplantation. Here, we found low expression of PRDM1 in T cells from donor and recipients both related to the occurrence of acute graft-versus-...

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Detalles Bibliográficos
Autores principales: Guo, Huidong, Wang, Ming, Wang, Bixia, Guo, Liping, Cheng, Yifei, Wang, Zhidong, Sun, Yu-Qian, Wang, Yu, Chang, Ying-Jun, Huang, Xiao-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097451/
https://www.ncbi.nlm.nih.gov/pubmed/35572579
http://dx.doi.org/10.3389/fimmu.2022.879501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097451/
https://www.ncbi.nlm.nih.gov/pubmed/35572579
http://dx.doi.org/10.3389/fimmu.2022.879501

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