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Brief Developmental Exposure to Fluoxetine Causes Life-Long Alteration of the Brain Transcriptome in Zebrafish

Fluoxetine (FLX) and other selective serotonin reuptake inhibitors are widely used to treat depressive disorders during pregnancy. Early-life exposure to FLX is known to disrupt the normal function of the stress axis in humans, rodents, and teleosts. We used a zebrafish line with a cortisol-inducibl...

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Detalles Bibliográficos
Autores principales: Nozari, Amin, Gagné, Remi, Lu, Chunyu, Yauk, Carole, Trudeau, Vance L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097470/
https://www.ncbi.nlm.nih.gov/pubmed/35573988
http://dx.doi.org/10.3389/fendo.2022.847322