Pd(II)-Catalyzed Enantioselective C(sp(3))–H Arylation of Cyclopropanes and Cyclobutanes Guided by Tertiary Alkylamines

[Image: see text] Strained aminomethyl-cycloalkanes are a recurrent scaffold in medicinal chemistry due to their unique structural features that give rise to a range of biological properties. Here, we report a palladium-catalyzed enantioselective C(sp(3))–H arylation of aminomethyl-cyclopropanes and...

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Detalles Bibliográficos
Autores principales: Rodrigalvarez, Jesus, Reeve, Luke A., Miró, Javier, Gaunt, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097487/
https://www.ncbi.nlm.nih.gov/pubmed/35212219
http://dx.doi.org/10.1021/jacs.1c11921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097487/
https://www.ncbi.nlm.nih.gov/pubmed/35212219
http://dx.doi.org/10.1021/jacs.1c11921

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