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Pd(II)-Catalyzed Enantioselective C(sp(3))–H Arylation of Cyclopropanes and Cyclobutanes Guided by Tertiary Alkylamines

[Image: see text] Strained aminomethyl-cycloalkanes are a recurrent scaffold in medicinal chemistry due to their unique structural features that give rise to a range of biological properties. Here, we report a palladium-catalyzed enantioselective C(sp(3))–H arylation of aminomethyl-cyclopropanes and...

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Detalles Bibliográficos
Autores principales:	Rodrigalvarez, Jesus, Reeve, Luke A., Miró, Javier, Gaunt, Matthew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097487/ https://www.ncbi.nlm.nih.gov/pubmed/35212219 http://dx.doi.org/10.1021/jacs.1c11921

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