Immunocapture sample clean-up in determination of low abundant protein biomarkers – a feasibility study of peptide capture by anti-protein antibodies

Immunocapture in mass spectrometry based targeted protein analysis using a bottom-up workflow is nowadays mainly performed by target protein extraction using anti-protein antibodies followed by tryptic digestion. Already available monoclonal antibodies (mAbs) which were developed against intact targ...

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Detalles Bibliográficos
Autores principales: Levernæs, Maren C. S., Farhat, Bassem, Oulie, Inger, Abdullah, Sazan S., Paus, Elisabeth, Reubsaet, Léon, Halvorsen, Trine G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097496/
https://www.ncbi.nlm.nih.gov/pubmed/35702551
http://dx.doi.org/10.1039/c9ra05071j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097496/
https://www.ncbi.nlm.nih.gov/pubmed/35702551
http://dx.doi.org/10.1039/c9ra05071j

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