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Immunocapture sample clean-up in determination of low abundant protein biomarkers – a feasibility study of peptide capture by anti-protein antibodies
Immunocapture in mass spectrometry based targeted protein analysis using a bottom-up workflow is nowadays mainly performed by target protein extraction using anti-protein antibodies followed by tryptic digestion. Already available monoclonal antibodies (mAbs) which were developed against intact targ...
Autores principales: | Levernæs, Maren C. S., Farhat, Bassem, Oulie, Inger, Abdullah, Sazan S., Paus, Elisabeth, Reubsaet, Léon, Halvorsen, Trine G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097496/ https://www.ncbi.nlm.nih.gov/pubmed/35702551 http://dx.doi.org/10.1039/c9ra05071j |
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