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Mitotic Spindle Positioning (MISP) is an actin bundler that selectively stabilizes the rootlets of epithelial microvilli

Microvilli are conserved actin-based surface protrusions that have been repurposed throughout evolution to fulfill diverse cell functions. In the case of transporting epithelia, microvilli are supported by a core of actin filaments bundled in parallel by villin, fimbrin, and espin. Remarkably, micro...

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Detalles Bibliográficos
Autores principales: Morales, E. Angelo, Arnaiz, Cayetana, Krystofiak, Evan S., Zanic, Marija, Tyska, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097542/
https://www.ncbi.nlm.nih.gov/pubmed/35443169
http://dx.doi.org/10.1016/j.celrep.2022.110692