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Microsatellite Instability and Metastatic Colorectal Cancer – A Clinical Perspective

Approximately 4-5% of patients with metastatic colorectal cancer (mCRC) have mismatch repair deficient (dMMR)/microsatellite instability-high (MSI-H) tumours. These tumours present challenges in the clinical practice due to variant response to fluoropyrimidine-based chemotherapy and, perhaps, also n...

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Detalles Bibliográficos
Autor principal: Buchler, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097548/
https://www.ncbi.nlm.nih.gov/pubmed/35574322
http://dx.doi.org/10.3389/fonc.2022.888181