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Improving the Robustness of Engineered Bacteria to Nutrient Stress Using Programmed Proteolysis

[Image: see text] The use of short peptide tags in synthetic genetic circuits allows for the tuning of gene expression dynamics and release of amino acid resources through targeted protein degradation. Here, we use elements of the Escherichia coli and Mesoplasma florum transfer-mRNA (tmRNA) ribosome...

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Detalles Bibliográficos
Autores principales: Szydlo, Klara, Ignatova, Zoya, Gorochowski, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097571/
https://www.ncbi.nlm.nih.gov/pubmed/35174698
http://dx.doi.org/10.1021/acssynbio.1c00490