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Early prediction of incident liver disease using conventional risk factors and gut-microbiome-augmented gradient boosting

The gut microbiome has shown promise as a predictive biomarker for various diseases. However, the potential of gut microbiota for prospective risk prediction of liver disease has not been assessed. Here, we utilized shallow shotgun metagenomic sequencing of a large population-based cohort (N > 7,...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Méric, Guillaume, Havulinna, Aki S., Teo, Shu Mei, Åberg, Fredrik, Ruuskanen, Matti, Sanders, Jon, Zhu, Qiyun, Tripathi, Anupriya, Verspoor, Karin, Cheng, Susan, Jain, Mohit, Jousilahti, Pekka, Vázquez-Baeza, Yoshiki, Loomba, Rohit, Lahti, Leo, Niiranen, Teemu, Salomaa, Veikko, Knight, Rob, Inouye, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097589/
https://www.ncbi.nlm.nih.gov/pubmed/35354069
http://dx.doi.org/10.1016/j.cmet.2022.03.002