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Immune-mediated neurodegenerative trait provoked by multimodal derepression of long-interspersed nuclear element-1

Neurodegeneration is a process involving both cell autonomous and non-cell autonomous neuron loss, followed by a collapse of neural networks, but its pathogenesis is poorly understood. We have previously demonstrated that Eomes-positive helper T (Eomes + Th) cells recognizing LINE-1(L1)-derived prot...

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Detalles Bibliográficos
Autores principales: Takahashi, Fumio, Zhang, Chenyang, Hohjoh, Hirohiko, Raveney, Ben, Yamamura, Takashi, Hayashi, Nobuhiro, Oki, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097630/
https://www.ncbi.nlm.nih.gov/pubmed/35573205
http://dx.doi.org/10.1016/j.isci.2022.104278