Cargando…

Immune-mediated neurodegenerative trait provoked by multimodal derepression of long-interspersed nuclear element-1

Neurodegeneration is a process involving both cell autonomous and non-cell autonomous neuron loss, followed by a collapse of neural networks, but its pathogenesis is poorly understood. We have previously demonstrated that Eomes-positive helper T (Eomes + Th) cells recognizing LINE-1(L1)-derived prot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Takahashi, Fumio, Zhang, Chenyang, Hohjoh, Hirohiko, Raveney, Ben, Yamamura, Takashi, Hayashi, Nobuhiro, Oki, Shinji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097630/ https://www.ncbi.nlm.nih.gov/pubmed/35573205 http://dx.doi.org/10.1016/j.isci.2022.104278

Ejemplares similares

Pathogenic Microglia Orchestrate Neurotoxic Properties of Eomes-Expressing Helper T Cells
por: Zhang, Chenyang, et al.
Publicado: (2023)

Extrapituitary prolactin promotes generation of Eomes-positive helper T cells mediating neuroinflammation
por: Zhang, Chenyang, et al.
Publicado: (2019)

Eomesodermin-expressing T-helper cells are essential for chronic neuroinflammation
por: Raveney, Ben J. E., et al.
Publicado: (2015)

Nuclear Receptor NR4A2 Orchestrates Th17 Cell-Mediated Autoimmune Inflammation via IL-21 Signalling
por: Raveney, Ben J. E., et al.
Publicado: (2013)

Short Interspersed Element (SINE) Depletion and Long Interspersed Element (LINE) Abundance Are Not Features Universally Required for Imprinting
por: Cowley, Michael, et al.
Publicado: (2011)

Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis
por: Kimura, Kimitoshi, et al.
Publicado: (2018)

Attenuation of microRNA-16 derepresses the cyclins D1, D2 and E1 to provoke cardiomyocyte hypertrophy
por: Huang, Shuai, et al.
Publicado: (2015)

The Role for Exosomal microRNAs in Disruption of Regulatory T Cell Homeostasis in Multiple Sclerosis
por: Kimura, Kimitoshi, et al.
Publicado: (2018)

Extracellular Vesicles as Pro- and Anti-inflammatory Mediators, Biomarkers and Potential Therapeutic Agents in Multiple Sclerosis
por: Manu, Mallahalli. S, et al.
Publicado: (2021)

Derepression of the Plant Chromovirus LORE1 Induces Germline Transposition in Regenerated Plants
por: Fukai, Eigo, et al.
Publicado: (2010)

Modes of Retrotransposition of Long Interspersed Element-1 by Environmental Factors
por: Ishizaka, Yukihito, et al.
Publicado: (2012)

Retrotransposition of Long Interspersed Element 1 Induced by Methamphetamine or Cocaine
por: Okudaira, Noriyuki, et al.
Publicado: (2014)

Enterovirus Infection Restricts Long Interspersed Element 1 Retrotransposition
por: Li, Yan, et al.
Publicado: (2021)

MxB inhibits long interspersed element type 1 retrotransposition
por: Huang, Yu, et al.
Publicado: (2022)

Long interspersed nuclear element-1 hypomethylation in cancer: biology and clinical applications
por: Kitkumthorn, Nakarin, et al.
Publicado: (2011)

Long Interspersed Element–1 (LINE-1): Passenger or Driver in Human Neoplasms?
por: Rodić, Nemanja, et al.
Publicado: (2013)

Long interspersed nuclear element-1 expression and retrotransposition in prostate cancer cells
por: Briggs, Erica M., et al.
Publicado: (2018)

Neuropilin‐1 (NRP1) expression distinguishes self‐reactive helper T cells in systemic autoimmune disease
por: Raveney, Ben JE, et al.
Publicado: (2022)

Evolution of Two Short Interspersed Elements in Callorhinchus milii (Chondrichthyes, Holocephali) and Related Elements in Sharks and the Coelacanth
por: Luchetti, Andrea, et al.
Publicado: (2017)

Disease-Causing Allele-Specific Silencing by RNA Interference
por: Hohjoh, Hirohiko
Publicado: (2013)

Distribution, Diversity, and Long-Term Retention of Grass Short Interspersed Nuclear Elements (SINEs)
por: Mao, Hongliang, et al.
Publicado: (2017)

A comparative study of long interspersed element-1 protein immunoreactivity in cutaneous malignancies
por: Zolfaghari, Mohammad Ali, et al.
Publicado: (2020)

AnnoSINE: a short interspersed nuclear elements annotation tool for plant genomes
por: Li, Yang, et al.
Publicado: (2021)

Identification and functional characterization of the German cockroach, Blattella germanica, short interspersed nuclear elements
por: Firsov, Sergei Yu., et al.
Publicado: (2022)

Exonization of a deep intronic long interspersed nuclear element in Becker muscular dystrophy
por: Xie, Zhiying, et al.
Publicado: (2022)

Interspecific Comparison of Orthologous Short Interspersed Elements Loci Using Whole-Genome Data
por: Kosushkin, Sergei, et al.
Publicado: (2023)

Lectures on Anatomy, Interspersed with Practical Remarks
Publicado: (1831)

Lectures on Anatomy, Interspersed with Practical Remarks
Publicado: (1833)

Vegetation Dispersion, Interspersion, and Landscape Preference
por: Costa, Marco
Publicado: (2022)

EDIR: exome database of interspersed repeats
por: Vo Ngoc, Laura D T, et al.
Publicado: (2022)

PCR and Magnetic Bead-Mediated Target Capture for the Isolation of Short Interspersed Nucleotide Elements in Fishes
por: Liu, Dong, et al.
Publicado: (2012)

Association between long interspersed nuclear element-1 methylation levels and relapse in Wilms tumors
por: de Sá Pereira, Bruna M., et al.
Publicado: (2017)

Whole-genome expression analysis of mammalian-wide interspersed repeat elements in human cell lines
por: Carnevali, Davide, et al.
Publicado: (2017)

Effects of end-stage osteoarthritis on markers of skeletal muscle Long INterspersed Element-1 activity
por: Osburn, Shelby C., et al.
Publicado: (2022)

Involvement of cytotoxic Eomes-expressing CD4(+) T cells in secondary progressive multiple sclerosis
por: Raveney, Ben J. E., et al.
Publicado: (2021)

Reduction of Type IV Collagen by Upregulated miR-29 in Normal Elderly Mouse and klotho-Deficient, Senescence-Model Mouse
por: Takahashi, Masaki, et al.
Publicado: (2012)

Specific Inhibition of Tumor Cells by Oncogenic EGFR Specific Silencing by RNA interference
por: Takahashi, Masaki, et al.
Publicado: (2013)

FMRP, FXR1 protein and Dlg4 mRNA, which are associated with fragile X syndrome, are involved in the ubiquitin–proteasome system
por: Shimizu, Hideo, et al.
Publicado: (2023)

Methylation levels of the "long interspersed nucleotide element-1" repetitive sequences predict survival of melanoma patients
por: Sigalotti, Luca, et al.
Publicado: (2011)

Long Interspersed Nuclear Element-1 Hypomethylation and Oxidative Stress: Correlation and Bladder Cancer Diagnostic Potential
por: Patchsung, Maturada, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_li8ubs2n32uk4aebmsrboc9k74