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Medullary astrocytes mediate irregular breathing patterns generation in chronic heart failure through purinergic P2X7 receptor signalling

BACKGROUND: Breathing disorders (BD) (apnoeas/hypopneas, periodic breathing) are highly prevalent in chronic heart failure (CHF) and are associated with altered central respiratory control. Ample evidence identifies the retrotrapezoid nucleus (RTN) as an important chemosensitivity region for ventila...

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Detalles Bibliográficos
Autores principales: Toledo, Camilo, Díaz-Jara, Esteban, Diaz, Hugo S., Schwarz, Karla G., Pereyra, Katherin V., Las Heras, Alexandra, Rios-Gallardo, Angélica, Andrade, David C., Moreira, Thiago, Takakura, Ana, Marcus, Noah J., Del Rio, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097632/
https://www.ncbi.nlm.nih.gov/pubmed/35533501
http://dx.doi.org/10.1016/j.ebiom.2022.104044