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Interleukin-23 in the Pathogenesis of Inflammatory Bowel Disease and Implications for Therapeutic Intervention

The interleukin-23 [IL-23] cytokine, derived predominantly from macrophages and dendritic cells in response to microbial stimulation, has emerged as a critical promoter of chronic intestinal inflammation. Genome-wide association studies linking variants in IL23R to disease protection, bolstered by e...

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Detalles Bibliográficos
Autores principales: Sewell, Gavin W, Kaser, Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097674/
https://www.ncbi.nlm.nih.gov/pubmed/35553667
http://dx.doi.org/10.1093/ecco-jcc/jjac034