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Blockade of IL-23: What is in the Pipeline?

Interleukin 23 [IL-23] plays a key role in the pathogenesis of both Crohn’s disease [CD] and ulcerative colitis [UC], promoting a Th17 cell-related immune response. The combined blockade of IL-23 and IL-12 with ustekinumab has been demonstrated to be safe and effective in the treatment of inflammato...

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Detalles Bibliográficos
Autores principales: Parigi, Tommaso Lorenzo, Iacucci, Marietta, Ghosh, Subrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097679/
https://www.ncbi.nlm.nih.gov/pubmed/35553666
http://dx.doi.org/10.1093/ecco-jcc/jjab185