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Macrophages from gut-corrected CF mice express human CFTR and lack a pro-inflammatory phenotype

Macrophages represent prominent immune orchestrators of cystic fibrosis (CF) inflammation and, as such, are an ever-increasing focus of CF research with several reports of intrinsic immune dysfunction related to loss of CFTR activity in macrophages themselves. Animal models of CF have contributed, i...

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Detalles Bibliográficos
Autores principales: Gillan, Jonathan L, Hardisty, Gareth R, Davidson, Donald J, Gray, Robert D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097694/
https://www.ncbi.nlm.nih.gov/pubmed/34799297
http://dx.doi.org/10.1016/j.jcf.2021.11.004