Septin 9 and phosphoinositides regulate lysosome localization and their association with lipid droplets

The accumulation of lipid droplets (LDs) in the liver is a hallmark of steatosis, which is often associated with lysosomal dysfunction. Nevertheless, the underlying mechanisms remain unclear. Here, using Huh7 cells loaded with oleate as a model to study LD metabolism, we show that cellular content a...

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Detalles Bibliográficos
Autores principales: Song, Pei Xuan, Peng, Juan, Omrane, Mohyeddine, Cai, Ting ting, Samuel, Didier, Gassama-Diagne, Ama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097704/
https://www.ncbi.nlm.nih.gov/pubmed/35573204
http://dx.doi.org/10.1016/j.isci.2022.104288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097704/
https://www.ncbi.nlm.nih.gov/pubmed/35573204
http://dx.doi.org/10.1016/j.isci.2022.104288

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