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Multi-omics approach reveals posttranscriptionally regulated genes are essential for human pluripotent stem cells

The effects of transcription factors on the maintenance and differentiation of human-induced or embryonic pluripotent stem cells (iPSCs/ESCs) have been well studied. However, the importance of posttranscriptional regulatory mechanisms, which cause the quantitative dissociation of mRNA and protein ex...

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Detalles Bibliográficos
Autores principales: Iwasaki, Mio, Kawahara, Yuka, Okubo, Chikako, Yamakawa, Tatsuya, Nakamura, Michiko, Tabata, Tsuyoshi, Nishi, Yohei, Narita, Megumi, Ohta, Akira, Saito, Hirohide, Yamamoto, Takuya, Nakagawa, Masato, Yamanaka, Shinya, Takahashi, Kazutoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097716/
https://www.ncbi.nlm.nih.gov/pubmed/35573189
http://dx.doi.org/10.1016/j.isci.2022.104289