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p57(Kip2) imposes the reserve stem cell state of gastric chief cells

Adult stem cells constantly react to local changes to ensure tissue homeostasis. In the main body of the stomach, chief cells produce digestive enzymes; however, upon injury, they undergo rapid proliferation for prompt tissue regeneration. Here, we identified p57(Kip2) (p57) as a molecular switch fo...

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Detalles Bibliográficos
Autores principales: Lee, Ji-Hyun, Kim, Somi, Han, Seungmin, Min, Jimin, Caldwell, Brianna, Bamford, Aileen-Diane, Rocha, Andreia Sofia Batista, Park, JinYoung, Lee, Sieun, Wu, Szu-Hsien Sam, Lee, Heetak, Fink, Juergen, Pilat-Carotta, Sandra, Kim, Jihoon, Josserand, Manon, Szep-Bakonyi, Réka, An, Yohan, Ju, Young Seok, Philpott, Anna, Simons, Benjamin D., Stange, Daniel E., Choi, Eunyoung, Koo, Bon-Kyoung, Kim, Jong Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097776/
https://www.ncbi.nlm.nih.gov/pubmed/35523142
http://dx.doi.org/10.1016/j.stem.2022.04.001