Calpain‐1 mediates vascular remodelling and fibrosis via HIF‐1α in hypoxia‐induced pulmonary hypertension

Calpain‐1, a calcium‐activated neutral cysteine proteases, has been reported to be involved in the formation of pulmonary hypertension. HIF‐1α, an oxygen‐sensitive transcription factor, has been reported to activate genes involved in cell proliferation and extracellular matrix recombination. This st...

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Detalles Bibliográficos
Autores principales: Deng, Haiyan, Tian, Xiaoxue, Sun, Hening, Liu, Huan, Lu, Meili, Wang, Hongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097838/
https://www.ncbi.nlm.nih.gov/pubmed/35365973
http://dx.doi.org/10.1111/jcmm.17295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097838/
https://www.ncbi.nlm.nih.gov/pubmed/35365973
http://dx.doi.org/10.1111/jcmm.17295

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