ASIC1a stimulates the resistance of human hepatocellular carcinoma by promoting EMT via the AKT/GSK3β/Snail pathway driven by TGFβ/Smad signals

Multidrug resistance is the main obstacle to curing hepatocellular carcinoma (HCC). Acid‐sensing ion channel 1a (ASIC1a) has critical roles in all stages of cancer progression, especially invasion and metastasis, and in resistance to therapy. Epithelial to mesenchymal transition (EMT) transforms epi...

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Detalles Bibliográficos
Autores principales: Zhang, Yinci, Cao, Niandie, Gao, Jiafeng, Liang, Jiaojiao, Liang, Yong, Xie, Yinghai, Zhou, Shuping, Tang, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097844/
https://www.ncbi.nlm.nih.gov/pubmed/35426224
http://dx.doi.org/10.1111/jcmm.17288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097844/
https://www.ncbi.nlm.nih.gov/pubmed/35426224
http://dx.doi.org/10.1111/jcmm.17288

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