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Adenovirus type 5 SARS-CoV-2 vaccines delivered orally or intranasally reduced disease severity and transmission in a hamster model

Transmission-blocking strategies that slow the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and protect against coronavirus disease 2019 (COVID-19) are needed. We have developed an orally-delivered Adenovirus type (Ad) 5-vectored SARS-CoV-2 vaccine candidate that expresses...

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Detalles Bibliográficos
Autores principales: Langel, Stephanie N., Johnson, Susan, Martinez, Clarissa I., Tedjakusuma, Sarah N., Peinovich, Nadine, Dora, Emery G., Kuehl, Philip J., Irshad, Hammad, Barrett, Edward G., Werts, Adam, Tucker, Sean N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097881/
https://www.ncbi.nlm.nih.gov/pubmed/35511920
http://dx.doi.org/10.1126/scitranslmed.abn6868