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A novel 3-acyl isoquinolin-1(2H)-one induces G2 phase arrest, apoptosis and GSDME-dependent pyroptosis in breast cancer

Breast cancer is the most common malignancy among women worldwide, accordingly, numerous chemotherapeutic drugs have been discovered thus far. However, the development and application of these drugs is severely constrained because of their unclear mechanism. To address this issue, our previous work...

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Detalles Bibliográficos
Autores principales: Ma, Lei, Bian, Mengyao, Gao, Hui, Zhou, Zhi, Yi, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098002/
https://www.ncbi.nlm.nih.gov/pubmed/35551332
http://dx.doi.org/10.1371/journal.pone.0268060