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Protein degradation sets the fraction of active ribosomes at vanishing growth

Growing cells adopt common basic strategies to achieve optimal resource allocation under limited resource availability. Our current understanding of such “growth laws” neglects degradation, assuming that it occurs slowly compared to the cell cycle duration. Here we argue that this assumption cannot...

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Detalles Bibliográficos
Autores principales: Calabrese, Ludovico, Grilli, Jacopo, Osella, Matteo, Kempes, Christopher P., Lagomarsino, Marco Cosentino, Ciandrini, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098079/
https://www.ncbi.nlm.nih.gov/pubmed/35500024
http://dx.doi.org/10.1371/journal.pcbi.1010059