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Survival of HT29 cancer cells is influenced by hepatocyte growth factor receptor inhibition through modulation of self-DNA-triggered TLR9-dependent autophagy response

HGFR activation drives the malignant progression of colorectal cancer, and its inhibition displays anti-autophagic activity. The interrelated role of HGFR inhibition and TLR9/autophagy signaling in HT29 cancer cells subjected to modified self-DNA treatments has not been clarified. We analyzed this c...

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Detalles Bibliográficos
Autores principales: Bohusné Barta, Bettina, Simon, Ágnes, Nagy, Lőrinc, Dankó, Titanilla, Raffay, Regina Eszter, Petővári, Gábor, Zsiros, Viktória, Sebestyén, Anna, Sipos, Ferenc, Műzes, Györgyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098092/
https://www.ncbi.nlm.nih.gov/pubmed/35551547
http://dx.doi.org/10.1371/journal.pone.0268217