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How the ends signal the end: Regulation by E3 ubiquitin ligases recognizing protein termini
Specificity of eukaryotic protein degradation is determined by E3 ubiquitin ligases and their selective binding to protein motifs, termed “degrons,” in substrates for ubiquitin-mediated proteolysis. From the discovery of the first substrate degron and the corresponding E3 to a flurry of recent studi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098119/ https://www.ncbi.nlm.nih.gov/pubmed/35247307 http://dx.doi.org/10.1016/j.molcel.2022.02.004 |