Linkage reprogramming by tailor-made E3s reveals polyubiquitin chain requirements in DNA-damage bypass

A polyubiquitin chain can adopt a variety of shapes, depending on how the ubiquitin monomers are joined. However, the relevance of linkage for the signaling functions of polyubiquitin chains is often poorly understood because of our inability to control or manipulate this parameter in vivo. Here, we...

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Detalles Bibliográficos
Autores principales: Wegmann, Sabrina, Meister, Cindy, Renz, Christian, Yakoub, George, Wollscheid, Hans-Peter, Takahashi, Diane T., Mikicic, Ivan, Beli, Petra, Ulrich, Helle D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Technology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098123/
https://www.ncbi.nlm.nih.gov/pubmed/35263628
http://dx.doi.org/10.1016/j.molcel.2022.02.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098123/
https://www.ncbi.nlm.nih.gov/pubmed/35263628
http://dx.doi.org/10.1016/j.molcel.2022.02.016

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