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Linkage reprogramming by tailor-made E3s reveals polyubiquitin chain requirements in DNA-damage bypass
A polyubiquitin chain can adopt a variety of shapes, depending on how the ubiquitin monomers are joined. However, the relevance of linkage for the signaling functions of polyubiquitin chains is often poorly understood because of our inability to control or manipulate this parameter in vivo. Here, we...
Autores principales: | Wegmann, Sabrina, Meister, Cindy, Renz, Christian, Yakoub, George, Wollscheid, Hans-Peter, Takahashi, Diane T., Mikicic, Ivan, Beli, Petra, Ulrich, Helle D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098123/ https://www.ncbi.nlm.nih.gov/pubmed/35263628 http://dx.doi.org/10.1016/j.molcel.2022.02.016 |
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