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Targeting Genetic Modifiers of HBG Gene Expression in Sickle Cell Disease: The miRNA Option

Sickle cell disease (SCD) is one of the most common inherited hemoglobinopathy disorders that affects millions of people worldwide. Reactivation of HBG (HBG1, HBG2) gene expression and induction of fetal hemoglobin (HbF) is an important therapeutic strategy for ameliorating the clinical symptoms and...

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Detalles Bibliográficos
Autores principales: Starlard-Davenport, Athena, Gu, Qingqing, Pace, Betty S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098152/
https://www.ncbi.nlm.nih.gov/pubmed/35553407
http://dx.doi.org/10.1007/s40291-022-00589-z