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Targeting Genetic Modifiers of HBG Gene Expression in Sickle Cell Disease: The miRNA Option
Sickle cell disease (SCD) is one of the most common inherited hemoglobinopathy disorders that affects millions of people worldwide. Reactivation of HBG (HBG1, HBG2) gene expression and induction of fetal hemoglobin (HbF) is an important therapeutic strategy for ameliorating the clinical symptoms and...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098152/ https://www.ncbi.nlm.nih.gov/pubmed/35553407 http://dx.doi.org/10.1007/s40291-022-00589-z |