High Yielding Continuous-Flow Synthesis of Norketamine

[Image: see text] A new continuous-flow process is presented for synthesis of the pharmaceutical intermediate norketamine (5). Our approach has been to take the well-established and industrially applied batch synthetic route to this promising antidepressant precursor and convert it to a telescoped m...

Descripción completa

Detalles Bibliográficos
Autores principales: Hernando, Marcos Veguillas, Moore, Jonathan C., Howie, Rowena A., Castledine, Richard A., Bourne, Samuel L., Jenkins, Gareth N., Licence, Peter, Poliakoff, Martyn, George, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098192/
https://www.ncbi.nlm.nih.gov/pubmed/35573033
http://dx.doi.org/10.1021/acs.oprd.1c00407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098192/
https://www.ncbi.nlm.nih.gov/pubmed/35573033
http://dx.doi.org/10.1021/acs.oprd.1c00407

Ejemplares similares