Thioredoxin-Interacting Protein (TXNIP) Knockdown Protects against Sepsis-Induced Brain Injury and Cognitive Decline in Mice by Suppressing Oxidative Stress and Neuroinflammation

Sepsis-associated encephalopathy (SAE) is linked to increased morbidity and mortality rates in patients with sepsis. Increased cytokine production and neuronal apoptosis are implicated in the pathogenesis of the SAE. Neuroinflammation plays a major role in sepsis-induced brain injury. Thioredoxin-in...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Xing, Cheng-Jun, Liu, Xiao, Li, Ya-Hong, Jia, Jing, Feng, Jian-Guo, Yang, Cheng-Jie, Chen, Ye, Zhou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098358/
https://www.ncbi.nlm.nih.gov/pubmed/35571246
http://dx.doi.org/10.1155/2022/8645714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098358/
https://www.ncbi.nlm.nih.gov/pubmed/35571246
http://dx.doi.org/10.1155/2022/8645714

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