Gadoxetic acid-enhanced magnetic resonance imaging predicts hyperbilirubinemia induced by glecaprevir during hepatitis C virus treatment

Glecaprevir is a substrate for organic anion-transporting polypeptide (OATP) 1B1/1B3, which transports bilirubin. Hyperbilirubinemia is an adverse event during anti-hepatitis C virus treatment with glecaprevir and pibrentasvir. Gadoxetic acid is also transported by OATP1B1/1B3, and we aimed to evalu...

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Detalles Bibliográficos
Autores principales: Okubo, Hironao, Atsukawa, Masanori, Okubo, Tomomi, Ando, Hitoshi, Nakadera, Eisuke, Ikejima, Kenichi, Nagahara, Akihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098462/
https://www.ncbi.nlm.nih.gov/pubmed/35552472
http://dx.doi.org/10.1038/s41598-022-11707-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098462/
https://www.ncbi.nlm.nih.gov/pubmed/35552472
http://dx.doi.org/10.1038/s41598-022-11707-6

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