Substrate recognition and cryo-EM structure of the ribosome-bound TAC toxin of Mycobacterium tuberculosis

Toxins of toxin-antitoxin systems use diverse mechanisms to control bacterial growth. Here, we focus on the deleterious toxin of the atypical tripartite toxin-antitoxin-chaperone (TAC) system of Mycobacterium tuberculosis, whose inhibition requires the concerted action of the antitoxin and its dedic...

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Detalles Bibliográficos
Autores principales: Mansour, Moise, Giudice, Emmanuel, Xu, Xibing, Akarsu, Hatice, Bordes, Patricia, Guillet, Valérie, Bigot, Donna-Joe, Slama, Nawel, D’urso, Gaetano, Chat, Sophie, Redder, Peter, Falquet, Laurent, Mourey, Lionel, Gillet, Reynald, Genevaux, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098466/
https://www.ncbi.nlm.nih.gov/pubmed/35552387
http://dx.doi.org/10.1038/s41467-022-30373-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098466/
https://www.ncbi.nlm.nih.gov/pubmed/35552387
http://dx.doi.org/10.1038/s41467-022-30373-w

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