Neuroligin-mediated neurodevelopmental defects are induced by mitochondrial dysfunction and prevented by lutein in C. elegans

Complex-I-deficiency represents the most frequent pathogenetic cause of human mitochondriopathies. Therapeutic options for these neurodevelopmental life-threating disorders do not exist, partly due to the scarcity of appropriate model systems to study them. Caenorhabditis elegans is a genetically tr...

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Detalles Bibliográficos
Autores principales: Maglioni, Silvia, Schiavi, Alfonso, Melcher, Marlen, Brinkmann, Vanessa, Luo, Zhongrui, Laromaine, Anna, Raimundo, Nuno, Meyer, Joel N., Distelmaier, Felix, Ventura, Natascia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098500/
https://www.ncbi.nlm.nih.gov/pubmed/35551180
http://dx.doi.org/10.1038/s41467-022-29972-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098500/
https://www.ncbi.nlm.nih.gov/pubmed/35551180
http://dx.doi.org/10.1038/s41467-022-29972-4

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