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Computational studies evidenced the potential of steroidal lactone to disrupt surface interaction of SARS-CoV-2 spike protein and hACE2

The critical event in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogenesis is recognition of host cells by the virus, which is facilitated by protein-protein interaction (PPI) of viral Spike-Receptor Binding Domain (S-RBD) and Human Angiotensin Converting Enzyme 2-Receptor (hACE...

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Detalles Bibliográficos
Autores principales: Yadav, Ajay, Ojha, Monu Dinesh, Hariprasad, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098575/
https://www.ncbi.nlm.nih.gov/pubmed/35596971
http://dx.doi.org/10.1016/j.compbiomed.2022.105598