Blockade of Myd88 signaling by a novel MyD88 inhibitor prevents colitis-associated colorectal cancer development by impairing myeloid-derived suppressor cells

Background. In cancer, myeloid-derived suppressor cells (MDSCs) are known to escape the host immune system by developing a highly suppressive environment. However, little is known about the molecular mechanism behind MDSC-mediated tumor cell evasion of the immune system. Toll-like receptor (TLR) sig...

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Detalles Bibliográficos
Autores principales: Wang, Lu, Hu, Dan, Xie, Bin, Xie, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Preclinical Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098617/
https://www.ncbi.nlm.nih.gov/pubmed/35089465
http://dx.doi.org/10.1007/s10637-022-01218-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098617/
https://www.ncbi.nlm.nih.gov/pubmed/35089465
http://dx.doi.org/10.1007/s10637-022-01218-6

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