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Validated determination of NRG1 Ig-like domain structure by mass spectrometry coupled with computational modeling

High resolution hydroxyl radical protein footprinting (HR-HRPF) is a mass spectrometry-based method that measures the solvent exposure of multiple amino acids in a single experiment, offering constraints for experimentally informed computational modeling. HR-HRPF-based modeling has previously been u...

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Detalles Bibliográficos
Autores principales: Khaje, Niloofar Abolhasani, Eletsky, Alexander, Biehn, Sarah E., Mobley, Charles K., Rogals, Monique J., Kim, Yoonkyoo, Mishra, Sushil K., Doerksen, Robert J., Lindert, Steffen, Prestegard, James H., Sharp, Joshua S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098640/
https://www.ncbi.nlm.nih.gov/pubmed/35551273
http://dx.doi.org/10.1038/s42003-022-03411-y