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Validated determination of NRG1 Ig-like domain structure by mass spectrometry coupled with computational modeling
High resolution hydroxyl radical protein footprinting (HR-HRPF) is a mass spectrometry-based method that measures the solvent exposure of multiple amino acids in a single experiment, offering constraints for experimentally informed computational modeling. HR-HRPF-based modeling has previously been u...
Autores principales: | Khaje, Niloofar Abolhasani, Eletsky, Alexander, Biehn, Sarah E., Mobley, Charles K., Rogals, Monique J., Kim, Yoonkyoo, Mishra, Sushil K., Doerksen, Robert J., Lindert, Steffen, Prestegard, James H., Sharp, Joshua S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098640/ https://www.ncbi.nlm.nih.gov/pubmed/35551273 http://dx.doi.org/10.1038/s42003-022-03411-y |
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