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Reconstruct high-resolution 3D genome structures for diverse cell-types using FLAMINGO

High-resolution reconstruction of spatial chromosome organizations from chromatin contact maps is highly demanded, but is hindered by extensive pairwise constraints, substantial missing data, and limited resolution and cell-type availabilities. Here, we present FLAMINGO, a computational method that...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Yang, Jiaxin, Zhang, Yu, Qian, Jianliang, Wang, Jianrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098643/
https://www.ncbi.nlm.nih.gov/pubmed/35551182
http://dx.doi.org/10.1038/s41467-022-30270-2