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Reconstruct high-resolution 3D genome structures for diverse cell-types using FLAMINGO
High-resolution reconstruction of spatial chromosome organizations from chromatin contact maps is highly demanded, but is hindered by extensive pairwise constraints, substantial missing data, and limited resolution and cell-type availabilities. Here, we present FLAMINGO, a computational method that...
Autores principales: | Wang, Hao, Yang, Jiaxin, Zhang, Yu, Qian, Jianliang, Wang, Jianrong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098643/ https://www.ncbi.nlm.nih.gov/pubmed/35551182 http://dx.doi.org/10.1038/s41467-022-30270-2 |
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