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Molecular insights into biogenesis of glycosylphosphatidylinositol anchor proteins

Eukaryotic cells are coated with an abundance of glycosylphosphatidylinositol anchor proteins (GPI-APs) that play crucial roles in fertilization, neurogenesis, and immunity. The removal of a hydrophobic signal peptide and covalent attachment of GPI at the new carboxyl terminus are catalyzed by an en...

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Detalles Bibliográficos
Autores principales: Xu, Yidan, Jia, Guowen, Li, Tingting, Zhou, Zixuan, Luo, Yitian, Chao, Yulin, Bao, Juan, Su, Zhaoming, Qu, Qianhui, Li, Dianfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098846/
https://www.ncbi.nlm.nih.gov/pubmed/35551457
http://dx.doi.org/10.1038/s41467-022-30250-6