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Tim-3(+) decidual Mφs induced Th2 and Treg bias in decidual CD4(+)T cells and promoted pregnancy maintenance via CD132
T-cell immunoglobulin mucin-3 (Tim-3) plays roles in the functional regulation of both adaptive and innate immune cells and is greatly involved in many diseases. However, the precise roles of Tim-3 on macrophages (Mφs) in pregnancy remain unstated. In the current study, we found the higher frequency...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098864/ https://www.ncbi.nlm.nih.gov/pubmed/35550500 http://dx.doi.org/10.1038/s41419-022-04899-2 |