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Tim-3(+) decidual Mφs induced Th2 and Treg bias in decidual CD4(+)T cells and promoted pregnancy maintenance via CD132

T-cell immunoglobulin mucin-3 (Tim-3) plays roles in the functional regulation of both adaptive and innate immune cells and is greatly involved in many diseases. However, the precise roles of Tim-3 on macrophages (Mφs) in pregnancy remain unstated. In the current study, we found the higher frequency...

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Detalles Bibliográficos
Autores principales: Li, Mengdie, Sun, Fengrun, Xu, Yuanyuan, Chen, Lanting, Chen, Chunqin, Cui, Liyuan, Qian, Jinfeng, Li, Dajin, Wang, Songcun, Du, Meirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098864/
https://www.ncbi.nlm.nih.gov/pubmed/35550500
http://dx.doi.org/10.1038/s41419-022-04899-2