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Effects of rhBMP-2-loaded hydroxyapatite granules/beta-tricalcium phosphate hydrogel (HA/β-TCP/hydrogel) composite on a rat model of caudal intervertebral fusion

The effects and inflammation-related side effects of bone morphogenetic protein (BMP)-2 on posterior lumbar interbody fusion are controversial. One of the potential causes for the inconsistent results is the uncontrolled release of BMP-2 from the collagen carrier. Therefore, BMP delivery systems tha...

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Detalles Bibliográficos
Autores principales: Nakagawa, Shinichi, Okada, Rintaro, Kushioka, Junichi, Kodama, Joe, Tsukazaki, Hiroyuki, Bal, Zeynep, Tateiwa, Daisuke, Ukon, Yuichiro, Hirai, Hiromasa, Makino, Takahiro, Takenaka, Shota, Okada, Seiji, Kaito, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098867/
https://www.ncbi.nlm.nih.gov/pubmed/35550600
http://dx.doi.org/10.1038/s41598-022-12082-y