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Biophysical and functional study of CRL5(Ozz), a muscle specific ubiquitin ligase complex

Ozz, a member of the SOCS-box family of proteins, is the substrate-binding component of CRL5(Ozz), a muscle-specific Cullin-RING ubiquitin ligase complex composed of Elongin B/C, Cullin 5 and Rbx1. CRL5(Ozz) targets for proteasomal degradation selected pools of substrates, including sarcolemma-assoc...

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Detalles Bibliográficos
Autores principales: Campos, Yvan, Nourse, Amanda, Tanwar, Ajay, Kalathur, Ravi, Bonten, Erik, d’Azzo, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098882/
https://www.ncbi.nlm.nih.gov/pubmed/35551201
http://dx.doi.org/10.1038/s41598-022-10955-w